Phorbol 12-myristate 13-acetate( PMA )

Catalog No. M12527 CAS No. 16561-29-8

A PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms.

Purity : >98% (HPLC)

COA

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Biological Information

Product Name

Phorbol 12-myristate 13-acetate
Note

Research use only, not for human use.
Brief Description

A PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms.
Description

A PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms; a potent tumor promoter often employed in biomedical research.
In Vitro

——
In Vivo

——
Synonyms

PMA
Pathway

Angiogenesis
Target

PKC
Recptor

PKC
Research Area

Inflammation/Immunology
Indication

——

Chemical Information

CAS Number

16561-29-8
Formula Weight

616.825
Molecular Formula

C36H56O8
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 62 mg/mL
SMILES

CCCCCCCCCCCCCC(O[C@]1([H])[C@@]([C@@]2(O)[C@@]([C@]([C@@]13OC(C)=O)([H])C3(C)C)([H])C=C(CO)C[C@@]4(O)[C@@]2([H])C=C(C4=O)C)([H])C)=O
Chemical Name

Tetradecanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Xu F, et al. Br J Pharmacol. 2003 Sep;140(2):413-21. 2. Blumberg PM, et al. Cancer Res. 1988 Jan 1;48(1):1-8. 3. Niedel JE, et al. Proc Natl Acad Sci U S A. 1983 Jan;80(1):36-40.

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